Recent public hearings on misconduct charges belie the conjecture that due process will perforce defeat informed scientific reasoning. One notable case that reviewed an obtuse description of experimental methods displays some of the subtleties of differentiating carelessness from intent to deceive. There the decision of a studious nonscientist panel managed to reach sensible conclusions despite conflicting expert testimony. The significance of such a result may be to suggest that to curtail due process would be both objectionable and unproductive.

Music can reduce stress and anxiety, enhance positive mood, and facilitate social bonding. However, little is known about the role of music and related personal or cultural variables in maintaining wellbeing during times of stress and social isolation as imposed by the COVID-19 crisis. In an online questionnaire, administered in 11 countries, participants rated the relevance of wellbeing goals during the pandemic, and the effectiveness of different activities in obtaining these goals. Music was found to be the most effective activity (...) for three out of five wellbeing goals: enjoyment, venting negative emotions, and self-connection. For diversion, music was equally good as entertainment, while it was second best to create a sense of togetherness, after socialization. This result was evident across different countries and gender, with minor effects of age on specific goals, and a clear effect of the importance of music in people's lives. Cultural effects were generally small and surfaced mainly in the use of music to obtain a sense of togetherness. Interestingly, culture moderated the use of negatively valenced and nostalgic music for those higher in distress. (shrink)

New concepts may prove necessary to profit from the avalanche of sequence data on the genome, transcriptome, proteome and interactome and to relate this information to cell physiology. Here, we focus on the concept of large activity-based structures, or hyperstructures, in which a variety of types of molecules are brought together to perform a function. We review the evidence for the existence of hyperstructures responsible for the initiation of DNA replication, the sequestration of newly replicated origins of replication, cell division (...) and for metabolism. The processes responsible for hyperstructure formation include changes in enzyme affinities due to metabolite-induction, lipid-protein affinities, elevated local concentrations of proteins and their binding sites on DNA and RNA, and transertion. Experimental techniques exist that can be used to study hyperstructures and we review some of the ones less familiar to biologists. Finally, we speculate on how a variety of in silico approaches involving cellular automata and multi-agent systems could be combined to develop new concepts in the form of an Integrated cell (I-cell) which would undergo selection for growth and survival in a world of artificial microbiology. (shrink)

This paper is addressed to recent theoretical discussions of the Anthropocene, in particular Bernard Stiegler’s Neganthropocene (Open Universities Press, 2018), which argues: “As we drift past tipping points that put future biota at risk, while a post-truth regime institutes the denial of ‘climate change’ (as fake news), and as Silicon Valley assistants snatch decision and memory, and as gene-editing and a financially-engineered bifurcation advances over the rising hum of extinction events and the innumerable toxins and conceptual opiates that Anthropocene (...) Talk fascinated itself with—in short, as ‘the Anthropocene’ discloses itself as a dead-end trap…”. The objective of this paper is therefore twofold: (1) to discuss how the Anthropocene is appropriated to certain ideological discourses (paradoxically) to maintain the hegemony of precisely those systems of production that have most accelerated climate change etc.; (2) to consider how the factography of the Anthropocene is exploited in this process to mask the ideological character of industry-aligned “technocratic” environmental management. The paper is not concerned with specific case studies in terms of government and industry policy, or climate science, but rather with the ways in which the discourse of the Anthropocene has been inflected within the humanities and the broader cultural field—that is to say, ideologically, as a system or logic of meaning. How the Anthropocene “means” is, in this respect, a question of some importance. This paper does not attempt to address all the facets of this question, but focuses upon a central “apocalyptic” strain in the discourse of the Anthropocene drawn particularly from Francis Fukuyama’s millennial posthumanism and centred in the question of “sustainability” as catastrophe management—with the risk that real environmental degradation will become an alibi for a revived neoliberalism. In other words, that the critical Earth system transformations that characterise the Anthropocene are themselves commodities, and that the project of their amelioration is in process of defining a future (opportunistic) “crisis” rhetoric with a global political franchise. The ideological import of the Anthropocene stems precisely from the fact that it is planetary and, while catalysed by human agency, independent in its specific behaviour from it. The Anthropocene objectively presents as the contemporary counterpart of the Cold War doctrine of Mutually Assured Destruction and the most compelling argument for a new kind of technological “arms race.” But it also presents as the condition of an emerging ideological discourse which will determine how this race is run. From the discourse on “energy security” to the widespread “security crackdown” on environmental activists across the so-called developed & developing world, the Anthropocene has come to represent the co-option of a scientific factography for the thinly disguised resurgence of “ideological science” of the Fukuyamaesque variety (post-history, post-human). For Fukuyama, the true meaning of “posthuman” is thus the accomplishment of humanity’s historical mission. As the “End of History” designates an end of ideological struggle, so too the dénouement of the Anthropocene and the “ends of man” represent the accomplished purpose of species warfare: dominion, not simply over the world, but over all possible worlds. According to this narrative, science—like technology—must be uniquely at the service of the maintenance of the global order, organised around a universal appeal to “crisis management.” It is precisely for this reason that what calls itself post-human masks the return of an ever-more-apocalyptic Humanism. (shrink)

For Louis Lavelle who wanted to write De la sagesse as a crowning of his work, the question of wisdom stands in the very centre of philosophy. The wise questions the meaning of existence. Thanks to wisdom, man, a free and temporal being, chooses the possible realities that bring him closer to Being. Wisdom in Lavelle’s sense is a wisdom of love, of mind and of being. The friend of wisdom, a man of reason and interiority, discovers in love (...) the summit and the essence of values. Lavelle’s thought on wisdom, gravitating around the notion of mind, brings together biblical, spiritual, mystic sources and purely philosophical sources. Both theoretical and practical, cultivating a Greek ideal of moderation and measure, wisdom aspires to the light of presence. (shrink)

Au début du XVIIIe siècle, une querelle éclate entre deux chimistes français à propos de la fabrication artificielle du fer. C’est en fait un conflit entre une interprétation mécaniste des processus chimiques et une approche plus traditionnelle, soupçonnée d’emprunter ses thèses à l’alchimie, mais qui sera pourtant à l’origine de la table des affinités qui sera adoptée par tous les chimistes jusqu’au début du XIXe siècle.

Part I: WHAT IS ETHICS? Plato: Socratic Morality: Crito. Suggestions for Further Reading. Part II: ETHICAL RELATIVISM VERSUS ETHICAL OBJECTIVISM. Herodotus: Custom is King. Thomas Aquinas: Objectivism: Natural Law. Ruth Benedict: A Defense of Ethical Relativism. Louis Pojman: A Critique of Ethical Relativism. Gilbert Harman: Moral Relativism Defended. Alan Gewirth: The Objective Status of Human Rights. Suggestions for Further Reading. Part III: MORALITY, SELF-INTEREST AND FUTURE SELVES. Plato: Why Be Moral? Richard Taylor: On the Socratic Dilemma. David Gauthier: Morality (...) and Advantage. Gregory Kavka: A Reconciliation Project. Derek Parfit: Later Selves and Moral Principles. Bernard Williams: Persons, Character, and Morality. Suggestions for Further Reading. Part IV: VALUE. Jeremy Bentham: Classical Hedonism. Robert Nozick: The Experience Machine. Richard Taylor: Value and the Origin of Right and Wrong. Friedrich Nietzsche: The Transvaluation of Values. Derek Parfit: What Makes Someone’s Life Go Best? Thomas Nagel: Value: The View from Nowhere. Suggestions for Further Reading. Part V: UTILITARIANISM AND CONSEQUENTIALISM. John Stuart Mill: Utilitarianism. J.J.C. Smart: Extreme and Restricted Utilitarianism. Kai Nielsen: Against Moral Conservatism. Bernard Williams: Against Utilitarianism. John Hospers: Rule-Utilitarianism. Robert Nozick: Side Constraints. Peter Singer: Famine, Affluence and Morality. Suggestions for Further Reading. Part VI: KANTIAN AND DEONTOLOGICAL SYSTEMS. Immanuel Kant: Foundation for the Metaphysic of Morals. W. D. Ross: What Makes Right Acts Right? Onora O’Neill: Kantian Formula of the End in Itself and World Hunger. Thomas Nagel: Moral Luck. Philippa Foot: Morality as a System of Hypothetical Imperatives. Judith Jarvis Thomson: Killing, Letting Die, and the Trolley Problem. Suggestions for Further Reading. Part VII: CONTRACTARIAN ETHICAL SYSTEMS. Thomas Hobbes: The Leviathan. David Gauthier: Why Contractarianism? John Rawls: Contractualism: Justice as Fairness. T.M. Scanlon: Contractualism and Utilitarianism. Suggestions for Further Reading. Part VIII: VIRTUE-BASED ETHICAL SYSTEMS. Aristotle: The Ethics of Virtue. Bernard Mayo: Virtue and the Moral Life. William Frankena: A Critique of Virtue-Based Ethics. Walter Schaller: Are Virtues No More than Dispositions to Obey Moral Rules? Alasdair MacIntyre: The Nature of the Virtues. Susan Wolf: Moral Saints. Louis P. Pojman: In Defense of Moral Saints. Suggestions for Further Reading. Part IX: THE FACT/VALUE PROBLEM: METAETHICS IN THE TWENTIETH CENTURY. David Hume: On Reason and the Emotions: The Fact/Value Distinction. G. E. Moore: Non-Naturalism. A. J. Ayer: Emotivism. R. M. Hare: Prescriptivism: The Structure of Ethics and Morals. Geoffrey Warnock: The Object of Morality. Suggestions for Further Reading. Part X: MORAL REALISM AND THE CHALLENGE OF SKEPTICISM. J.L. Mackie: The Subjectivity of Values. Jonathan Harrison: A Critique of Mackie’s Error Theory. Gilbert Harman: Moral Nihilism. Nicholas Sturgeon: Moral Explanations. Bernard Williams: Ethics and the Limits of Philosophy. Bruce Russell: Two Forms of Ethical Skepticism. Michael Smith: A Defense of Moral Realism. Suggestions for Further Reading. Part XI: RELIGION AND ETHICS. Plato: Morality and Religion. Immanuel Kant: God and Immortality as Necessary Postulates of Morality. George Mavrodes: Religious and the Queerness of Morality. Kai Nielson: Ethics Without God. Suggestions for Further Reading. Part XII: CONTEMPORARY CHALLENGES TO CLASSICAL ETHICAL THEORY. Part A. Sociobiology and the Question of Moral Responsibility. Charles Darwin: Ethics and the Descent of Man. E.O.Wilson: Sociobiology and Ethics. Michael Ruse: Evolution and Ethics: The Sociobiological Approach. Elliot Sober: Prospects for an Evolutionary Ethics. J.L. Mackie: The Law of the Jungle, Evolution and Morality. Suggestions for Further Readingon Sociobiology. Part B. The Challenge of Determinism to Moral Responsibility and Desert. Galen Strawson: The Impossibility of Moral Responsibility. Louis Pojman: Free Will, Determinism, and Moral Responsibility:A Response to Galen Strawson. Richard Taylor: A Libertarian Defense of Free Will and Responsibility. Suggestions for Further Reading on Moral Responsibility. Glossary of Ethical Terms. (shrink)

Louis Pojman and Robert Westmoreland have compiled the best material on the subject of equality, ranging from classical works by Aristotle, Hobbes and Rousseau to contemporary works by John Rawls, Thomas Nagel, Michael Walzer, Harry Frankfurt, Bernard Williams and Robert Nozick; and including such topics as: the concept of equality; equal opportunity; Welfare egalitarianism; resources; equal human rights and complex equality.

Bernard Lonergan was a Canadian Jesuit philosopher, theologian, and humanist who taught in Montreal, Toronto, Rome, and Boston. His groundbreaking works Insight: A Study of Human Understanding and Method in Theology attempt to discern how knowledge is advanced in the natural sciences, the human studies, the arts, ethics, and theology. In Engaging the Thought of Bernard Lonergan, Louis Roy stresses the empirical aspect of Lonergan’s cognitional theory in relation to the role of meaning, objectivity, subjectivity, and historical (...) consciousness. Rather than introducing every facet of his philosophy and theology, Roy delivers a balanced account of Lonergan’s achievements in fifteen discrete studies, delving into the implications of his cognitional theory for religious experience, theology, education, truth, classicism, relativism, and ethics. Discussing aspects of Lonergan’s thought that are seldom examined, these fifteen studies represent, criticize, and develop the ideas of one of the most important thinkers of the twentieth century. Demonstrating the richness of one scholar’s contributions to contemporary culture, Engaging the Thought of Bernard Lonergan presents a thoughtful analysis and a significant advance in Lonergan studies. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:September 27, 2008 (1:09 pm) G:\WPData\TYPE2801\russell 28,1 048RED.wpd 76 Reviews REAPPRAISING GILBERT MURRAY Louis Greenspan Religious Studies / McMaster U. Hamilton, on, Canada l8s 4k1 [email protected] ChristopherStray,ed.GilbertMurrayReassessed: Hellenism, Theatre, and International Politics. Oxford: Oxford U. P., 2007. Pp. xii, 400. £65; £27.50 (pb). Cdn. $156 (hb). us$55 (pb). isbn 978-0-19-920879-1 (hb). For much of the Wrst half of the twentieth century Gilbert Murray was a leading Wgure in (...) British academia, in British theatre, on the British and American lecture circuits and even in British politics. He was admired by the community of scholars as Regius Professor of Greek at Oxford, the most prestigious position in classical scholarship in the English-speaking world. He was also esteemed by a wider reading public as the champion of a magisterial liberalism rooted in classical Greek culture. Finally he was respected by the world at large as a liberal activist who, during World War 1, wrote well-argued pamphlets in support of the war and who later became co-chairman of the League of Nations Union, an organization that in the ’20s and ’30s attracted 400,000 members. Among his companions were George Bernard Shaw and Bertrand Russell, both of whom remained his friends for life. As chief editor of the Home University Library he commissioned Russell’s The Problems of Philosophyz, which is still unsurpassed as an introduction to this subject. Today he is forgotten. Younger classical scholars would endorse the statement by Fowler (quoted in this volume): “in spite of his great fame when he was alive, he might never have written, so far as most scholars are concerned today” (p. 58). His role as the public intellectual who connected modern liberalism with Hellenism has been taken over by the followers of Leo Strauss who view this connection rather diTerently than Murray did. As for his liberal activism, when he died in 1957 Murray was regarded aTectionately as a noble ghost of Victorian liberalism past, whose passionate advocacy of the League of Nations was seen as well meaning and futile as the organization he had championed. In the ’60s and ’70s his words and deeds were swept away in the tides of anti-liberal fervour that inspired the newly emerging leftist revolutionaries and neo-conservatives. At Wrst perusal Gilbert Murray Reassessed zhas the format of festschrifts and other scholarly reviews of the accomplishments of a particular writer. There are articles on every aspect of Murray’s activities: his translations of Greek drama, his critical editions of Euripides, his views of Hellenism, his post-World War 1 September 27, 2008 (1:09 pm) G:\WPData\TYPE2801\russell 28,1 048RED.wpd Reviews 77 internationalism and even his lectures on the bbc, all by specialists in these topics. But this volume is more than a summing up of Murray’s contributions to scholarship. The aim of the volume is to revive Murray the public intellectual, a voice of liberalism that deserves a new hearing. The book could have been entitled Gilbert Murray Retrieved for Our Timesz: a contribution to the struggle to Wnd a liberalism that addresses the anti-liberal, anti-intellectual forces that threaten us today. In this spirit the volume is dedicated to those who died in the London terrorist attack of July 2005. The volume opens with two sets of memoirs, one by Murray’s grandchildren Ann Pauladan and Alexander Murray, the other Francis West’s account of Murray ’s reXections on an Australian childhood. The memoirs of his grandchildren, aTectionate and charming, seem less interested in refashioning Gilbert Murray for our time. They still portray Murray as one who inhabited a world that is no more, the proponent of a liberalism that was naively optimistic and top heavy with reason at the expense of the emotions. Murray’s optimism is evident in their anecdote about an encounter between Murray and Sir Edward Grey, during a summer walk in 1914. Murray opened the conversation by scoUng at rumours of impending war in Europe, for him impossible between civilized powers. Grey closed it by assuring him that war was certain, thus causing the speechless and horriWed Murray... (shrink)

[Christianity] has enriched philosophy with far more definite and purer concepts than it had been able to furnish before; but which, once they are there, are freely assented to by Reason and are assumed as concepts to which it could well have come of itself and which it could and should have introduced…. Even the Holy One of the Gospel must first be compared with our ideal of moral perfection, before we can recognize him as such [Immanuel Kant, Critique of (...) Judgement, tr. Bernard; p. 410n and Foundations of the Metaphysics of Morals, tr. Lewis White Beck; p. 30]. (shrink)

Ces dernières années, plusieurs travaux sur l’histoire des femmes s’intéressent à leur présence et à leurs rôles dans les domaines artistiques laissés de côté par les ouvrages généraux plus anciens. Pour autant, des thèmes sont encore à explorer en ce qui concerne le rôle de certaines dans ces secteurs pour la période moderne. C’est le cas de la musique, pour laquelle des éléments sur la présence féminine sont décelables à travers des ouvrages sur l’art musical de cette période. Ainsi, l’ouvr...

We call attention to the historical fact that the meaning of symmetry in antiquity—as it appears in Vitruvius’s De architectura—is entirely different from the modern concept. This leads us to the question, what is the evidence for the changes in the meaning of the term symmetry, and what were the different meanings attached to it? We show that the meaning of the term in an aesthetic sense gradually shifted in the context of architecture before the image of the balance was (...) attached to the term in the middle of the 18th century and well before the first modern scientific usage by Legendre in 1794.Keywords: Symmetry; Vitruvius; Claude Perrault; Charles-Louis de Secondat Baron de Montesquieu; Balance in architecture. (shrink)

A very readable, scholarly, and provocative book by Louis Dupré gives a new interpretation and meaning to the passage to modernity. Dupre gives a fascinating hermeneutic analysis of the creative revolution achieved by the early and late humanists and thinkers of the Renaissance in rethinking reality in terms beyond the ancient and medieval ontotheological synthesis of God, the human, and the Cosmos. The book analyzes how the break leading into modernity took place at that time and prior to the (...) second modern revolution--the Enlightenment, when the transcendent component was disowned in favor of the human subject. Later, both were deprioritized in favor of the cosmos. (shrink)

O objetivo deste artigo é investigar a concepção enciclopédica de revolução científica posta em prática pelo químico francês L.-B. Guyton de Morveau (1737-1816). Deslocando a análise do conhecimento químico das Luzes do programa traçado por Lavoisier (1743-1794), sugerimos uma concepção revolucionária republicana, proclamada como resultado do esforço de uma coletividade. Daremos destaque a três abordagens revolucionárias de Guyton de Morveau no âmbito da química. A primeira foi sua atuação no ensino dessa ciência, cuja pedagogia e métodos de ensino foram fundamentais (...) para sua imersão social. Além disso, entre 1770 e 1790, Guyton de Morveau teve desempenhos decisivos no seio da empresa enciclopédica e no seio da escola química francesa. (shrink)

As we have seen, it was clearly Guyton's intention, in 1808, to supply details of his improved platinum pyrometer, and he did submit a drawing of the instrument at the meeting of the Class in December 1810. It would seem that on that occasion he did not supply those details which are to be found in the fourth, unpublished, part of the ‘Essay’. The existence of a text fit to be sent to the printer, and the execution of a drawing (...) relating to the improved version of his platinum pyrometer, might be taken as evidence that Guyton intended to publish. His paper of 1810 did not appear until 1814, however, so that publication of the fourth part of the ‘Essay’ could scarcely have occurred until 1815 or later. Guyton probably hoped to be able to read it to the Class of Physical and Mathematical Sciences before publishing it in the Annales de Chimie, but his death on 2 January 1816 robbed him of the opportunity. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:264 HISTORY OF PHILOSOPHY right at hand, without getting in the way. If it had been printed in as readable type and as elegant form as Steinmann's edition, it might be the ideal easily accessible version to familiarize us with the Pens~es as they were actually written and classified by Pascal himself. RICHARD H. POPKIN University of California, San Diego Pascal. Quinta edizione riveduta e aumentata. By Michele Federico (...) Sciacca. (Milano: Carlo Marzorati Editore, 1962. Pp. 250. 2000 L.) This Pascal by Sciacca consists of three parts. The first gives and considers the Life of Pascal (1623-1662) in connection with his complex and restless century (pp. 13--72). The second part (pp. 75-112) analyzes the relationship of Pascal with Jansenism. Pascal is both dependent on and independent of it. The Jansenists discussed while Pascal felt. Jansenism could not find a stable equilibrium between nature and grace which Jansenism either contrasted or confused while Pascal well distinguishes these two orders. They are for him heterogeneous but the lower order leads to the higher. Without God, man is misery and darkness. With God, man can do all things (p. 118). The third part (pp. 115-219) is entitled The Christian Philosopher. It shows that man is made for the infinite. The true call of humanity is religious (p. 206). The final conclusion is that Pascal can still teach us to exist (p. 216). PAUL Y. FUHRMANN Columbia Theological Seminary Louis Thomassin (1619-95), ~tude bio-bibliographique avec vingt lettres et deux textes in~dits. By Pierre Clair. (Vol. I of the series Le mouvement des idles au XVH" si~cle, Collection dirig~e par Andr~ Robinet.) (Paris: 1964. Pp. 160. NF 12.) This small volume is the first in a new series devoted to bringing to light various figures and aspects of seventeenth-century thought that have either been set aside, forgotten, or are only dimly known. Louis Thomassin (as well as Bernard Lamy who is the subject of the second volume that has appeared in this series) certainly falls in these categories. Although his name often turns up in discussions of Cartesianlsm, Jansenism, Malebranchism, etc., very little consideration is ever given to him as a fairly important personage of the time, or to his ideas and the role they played. This volume by Dr. Clair will be of much use to seventeenth-century scholars in providing the basic data about his life, his connections with several of the vital movements of the period, the fundamental bibliographical materials, as well as publishing two texts and twenty letters not before available. The biographical section (pp. 1-84) traces (a bit too episodically) Thomassin's education, his career among the Oratorians as a professor of humanities, philosophy, and theology, his possible involvements with the Jansenists, his difficulties as a result of his first published work, Dissertations sur les Conciles (1667) (suppressed the same year), his later successes for his many other works in theology, philosophy, history, and pedagogy, and his relations with various major and minor figures of the mid- and late seventeenth century, like Arnauld, Malebranche, Richard Simon, Bayle, Huet, etc. Section II (pp. 85-99) gives a detailed bibliography of Thomassin's published works, plus a list of his manuscripts located in various French libraries. This is followed by twenty letters of Thomassin, an intriguing and interesting discourse on the difference between history and science, and one on the nature of chronology, plus three letters by Thomassin's secretary, Nicolas Barat. In a brief BOOK REVIEWS 265 concluding chapter (pp. 150-52), Dr. Clair deals with "Comment lire l'oeuvre du P. Thomassin," providing much guidance to anyone who wishes to avail himself of the rich resources in Thomassin's writings. From the point of view of the history of philosophy, the most interesting aspects of Thomassin's thought seem to be (1) his "Cartesianism," that is, the extent to which he early imbibed Descartes' new ideas, and played a role in the fusion of the views of Augustine, B6rulle, and Descartes that developed in the Oratory, (2) his attempt to find a viable theory of the nature of Grace somewhere between Arnauld and Malebranche, and (3) his... (shrink)